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1

Developing a Virtual Adaptive Sports Program in Response to the COVID â19 Pandemic

Blauwet, Cheri A., Robinson, David, Riley, Alison, MacEwan, Keja, Patstone, Mary, Dubon, Mary E

Journal:

Year:

2020

File:

PDF, 1.48 MB

2020

2

Micro RNAs as a new therapeutic target towards leukaemia signalling

Megan Y. Murray, Stuart A. Rushworth, David J. MacEwan

Journal:

Cellular Signalling

Year:

2012

Language:

english

File:

PDF, 411 KB

english, 2012

3

Epigenetics and pharmacology

Stefanska, Barbara, MacEwan, David J

Journal:

British Journal of Pharmacology

Year:

2015

Language:

english

File:

PDF, 269 KB

english, 2015

4

[Methods in Pharmacology and Toxicology] Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases ||

Stefanska, Barbara, MacEwan, David J.

Year:

2017

Language:

english

File:

PDF, 4.16 MB

english, 2017

5

Hydroeconomic modeling of sustainable groundwater management

MacEwan, Duncan, Cayar, Mesut, Taghavi, Ali, Mitchell, David, Hatchett, Steve, Howitt, Richard

Journal:

Water Resources Research

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

6

Comparison of the Ottawa Surgical Competency Operating Room Evaluation (O-SCORE) to a Single-Item Performance Score

Saliken, David, Dudek, Nancy, Wood, Timothy J., MacEwan, Matthew, Gofton, Wade T.

Journal:

Teaching and Learning in Medicine

Year:

2018

Language:

english

File:

PDF, 1.23 MB

english, 2018

7

Pore forming polyalkylpyridinium salts from marine sponges versus synthetic lipofection systems: distinct tools for intracellular delivery of cDNA and siRNA

Debra McLaggan, Noppadon Adjimatera, Kristina Sepčić, Marcel Jaspars, David J MacEwan, Ian S Blagbrough, Roderick H Scott

Journal:

BMC Biotechnology

Year:

2006

Language:

english

File:

PDF, 1.24 MB

english, 2006

8

Phorbol ester and diacylglycerol activation of native protein kinase C species from various tissues

Melanie S. Johnson, James Simpson, David J. MacEwan, Angela Ison, Roger A. Clegg, Kevin Connor, Rory Mitchell

Journal:

Molecular and Cellular Biochemistry

Year:

1995

Language:

english

File:

PDF, 1.25 MB

english, 1995

9

Interactions between TNF and GnRH

David J. MacEwan

Journal:

Neurochemical Research

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

10

Tumour necrosis factor-α activates a calcium sensitization pathway in guinea-pig bronchial smooth muscle

James R. M. Parris, Hannah J. Cobban, Alison F. Littlejohn, David J. MacEwan, Graeme F. Nixon

Journal:

The Journal of Physiology

Year:

1999

Language:

english

File:

PDF, 1.55 MB

english, 1999

11

TNF ligands and receptors – a matter of life and death

David J MacEwan

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 692 KB

english, 2002

12

Selective down-regulation of the Cqα/G11α G-protein family in tumour necrosis factor-α induced cell death

Valerie Pollock, Elizabeth Lofthouse, Orla Jupp, Stephen Gauld, Helen Anderson, David MacEwan

Journal:

Molecular and Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 200 KB

english, 2000

13

Protein kinase C isoforms in pituitary cells displaying differential sensitivity to phorbol ester

David MacEwan, Melanie Johnson, Rory Mitchell

Journal:

Molecular and Cellular Biochemistry

Year:

1999

Language:

english

File:

PDF, 78 KB

english, 1999

14

Evidence that protein kinase Cα has reduced affinity towards 1,2-dioctanoyl-sn-glycerol: the effects of lipid activators on phorbol ester binding and kinase activity

David J. MacEwan, Rory Mitchell, Melanie S. Johnson, Fiona J. Thomson, Eve M. Lutz, Roger A. Clegg, Kevin Connor

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1993

Language:

english

File:

PDF, 917 KB

english, 1993

15

TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells

Zhigang Zhou, Michelle C. Connell, David J. MacEwan

Journal:

Cellular Signalling

Year:

2007

Language:

english

File:

PDF, 1.36 MB

english, 2007

16

Stimulation of stress-activated but not mitogen-activated protein kinases by tumour necrosis factor receptor subtypes in airway smooth muscle

Shona M. McFarlane, Orla J. Jupp, Hannah J. Cobban, Irene Hunter, Helen M. Anderson, Peter Vandenabeele, Graeme F. Nixon, David J. MacEwan

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 991 KB

english, 2001

17

Modulation by caspases of tumor necrosis factor-stimulated c-Jun N-terminal kinase activation but not nuclear factor-κB signaling

Alison F Littlejohn, Steven J Tucker, Ahmed A.A Mohamed, Stephen McKay, Matt J Helms, Peter Vandenabeele, David J MacEwan

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 439 KB

english, 2003

18

TNF receptor subtype signalling: Differences and cellular consequences

David J. MacEwan

Journal:

Cellular Signalling

Year:

2002

Language:

english

File:

PDF, 370 KB

english, 2002

19

Calcium influx through ‘L’-type channels into rat anterior pituitary cells can be modulated in two ways by protein kinase C (PKC-isoform selectivity of 1,2-dioctanoyl sn-glycerol?)

David J. MacEwan, Rory Mitchell

Journal:

Year:

1991

Language:

english

File:

PDF, 691 KB

english, 1991

20

Evidence for a distinct H7-resistant form of protein kinase C in rat anterior pituitary gland

Angela J. Ison, David J. MacEwan, Melanie S. Johnson, Roger A. Clegg, Kevin Connor, Rory Mitchell

Journal:

Year:

1993

Language:

english

File:

PDF, 742 KB

english, 1993

21

Characterisation of protein kinase C isoforms and enzymic activity from the αT3-1 gonadotroph-derived cell line

Melanie S. Johnson, David J. MacEwan, James Simpson, Rory Mitchell

Journal:

Year:

1993

Language:

english

File:

PDF, 809 KB

english, 1993

22

Elevated cPLA2 levels as a mechanism by which the p70 TNF and p75 NGF receptors enhance apoptosis

David J. MacEwan

Journal:

Year:

1996

Language:

english

File:

PDF, 590 KB

english, 1996

23

The influence of alkyl pyridinium sponge toxins on membrane properties, cytotoxicity, transfection and protein expression in mammalian cells

Steven J. Tucker, David McClelland, Marcel Jaspars, Kristina Sepčić, David J. MacEwan, Roderick H. Scott

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

2003

Language:

english

File:

PDF, 600 KB

english, 2003

24

Modulated kinase activities in cells undergoing tumour necrosis factor-induced apoptotic cell death

Matt J Helms, Ahmed A.A Mohamed, David J MacEwan

Journal:

Year:

2001

Language:

english

File:

PDF, 485 KB

english, 2001

25

Differential activation of nuclear factor-κB by tumour necrosis factor receptor subtypes. TNFR1 predominates whereas TNFR2 activates transcription poorly

Shona M McFarlane, Ghazaleh Pashmi, Michelle C Connell, Alison F Littlejohn, Steven J Tucker, Peter Vandenabeele, David J MacEwan

Journal:

Year:

2002

Language:

english

File:

PDF, 568 KB

english, 2002

26

Up-regulation of a constitutively active form of the β2-adrenoceptor by sustained treatment with inverse agonists but not antagonists

David J. MacEwan, Graeme Milligan

Journal:

Year:

1996

Language:

english

File:

PDF, 704 KB

english, 1996

27

Actions of cannabinoid receptor ligands on rat cultured sensory neurones: implications for antinociception

Ruth A Ross, Angela A Coutts, Shona M McFarlane, Sharon Anavi-Goffer, Andrew J Irving, Roger G Pertwee, David J MacEwan, Roderick H Scott

Journal:

Neuropharmacology

Year:

2001

Language:

english

File:

PDF, 448 KB

english, 2001

28

BTK inhibitor ibrutinib is cytotoxic to myeloma and potently enhances bortezomib and lenalidomide activities through NF-κB

Stuart A. Rushworth, Kristian M. Bowles, Lawrence N. Barrera, Megan Y. Murray, Lyubov Zaitseva, David J. MacEwan

Journal:

Cellular Signalling

Year:

2013

Language:

english

File:

PDF, 764 KB

english, 2013

29

Inhibition of depolarisation-induced calcium influx into GH3 cells by arachidonic acid: the involvement of protein kinase C

David J. MacEwan, Rory Mitchell, Fiona J. Thomson, Melanie S. Johnson

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1991

Language:

english

File:

PDF, 615 KB

english, 1991

30

The differential effects of protein kinase C activators and inhibitors on rat anterior pituitary hormone release

Thomson, Fiona J., Johnson, Melanie S., Mitchell, Rory, Wolbers, W.Bart, Ison, Angela J., MacEwan, David J.

Journal:

Molecular and Cellular Endocrinology

Year:

1993

Language:

english

File:

PDF, 1.48 MB

english, 1993

31

DUNDEE ROYAL INFIRMARY

Journal:

Year:

1896

Language:

english

File:

PDF, 398 KB

english, 1896

32

Efficient Synthesis of 8-Oxa-3-aza-bicyclo[3.2.1]octane Hydrochloride †

Connolly, Terrence J., Considine, John L., Ding, Zhixian, Forsatz, Brian, Jennings, Mellard N., MacEwan, Michael F., McCoy, Kevin M., Place, David W., Sharma, Archana, Sutherland, Karen

Journal:

Organic Process Research & Development

Year:

2010

Language:

english

File:

PDF, 1.92 MB

english, 2010

33

Emerging therapeutic aspects in oncology

MacEwan, David J

Journal:

British Journal of Pharmacology

Year:

2013

Language:

english

File:

PDF, 244 KB

english, 2013

34

Ibrutinib inhibits BTK-driven NF-κB p65 activity to overcome bortezomib-resistance in multiple myeloma

Murray, Megan Y, Zaitseva, Lyubov, Auger, Martin J, Craig, Jenny IO, MacEwan, David J, Rushworth, Stuart A, Bowles, Kristian M

Journal:

Year:

2015

Language:

english

File:

PDF, 2.74 MB

english, 2015

35

Activity of Bruton's tyrosine-kinase inhibitor ibrutinib in patients with CD117-positive acute myeloid leukaemia: a mechanistic study using patient-derived blast cells

Rushworth, Stuart A, Pillinger, Genevra, Abdul-Aziz, Amina, Piddock, Rachel, Shafat, Manar S, Murray, Megan Y, Zaitseva, Lyubov, Lawes, Matthew J, MacEwan, David J, Bowles, Kristian M

Journal:

The Lancet Haematology

Year:

2015

Language:

english

File:

PDF, 701 KB

english, 2015

36

The Role of Nrf2 and Cytoprotection in Regulating Chemotherapy Resistance of Human Leukemia Cells

Rushworth, Stuart A., MacEwan, David J.

Journal:

Year:

2011

Language:

english

File:

PDF, 395 KB

english, 2011

37

Attenuation of dexamethasone-induced cell death in multiple myeloma is mediated by miR-125b expression

Murray, Megan, Rushworth, Stuart A., Zaitseva, Lyubov, Bowles, Kristian M., MacEwan, David J.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.91 MB

english, 2013

38

Bortezomib induces heme oxygenase-1 expression in multiple myeloma

Barrera, Lawrence N., Rushworth, Stuart A., Bowles, Kristian M., MacEwan, David J.

Journal:

Year:

2012

Language:

english

File:

PDF, 577 KB

english, 2012

39

Interferon α Induces Protein Kinase C-ε (PKC- ε) Gene Expression and a 4.7-kb PKC-ε-Related Transcript

Chiang Wang, Stefan N. Constantinescu, David J. MacEwan, Berta Strulovici, Lodewijk V. Dekker, Peter J. Parker and Lawrence M. Pfeffer

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 1.03 MB

english, 1993

40

Silencing FLIP L modifies TNF-induced apoptotic protein expression

Zaitseva, Lyubov, Rushworth, Stuart A., MacEwan, David J.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.36 MB

english, 2011

41

TNF signaling gets FLIPped off: TNF-induced regulation of FLIP

Rushworth, Stuart A., Taylor, Alison, Langa, Susana, MacEwan, David J.

Journal:

Year:

2008

Language:

english

File:

PDF, 491 KB

english, 2008

42

Structural brain imaging abnormalities associated with schizophrenia and partial trisomy of chromosome 5

Honer, William G., Bassett, Anne S., MacEwan, G. William, Hurwitz, Trevor, Li, David K. B., Hilal, Sadek, Prohovnik, Isak

Journal:

Psychological Medicine

Year:

1992

Language:

english

File:

PDF, 1022 KB

english, 1992

43

A Canadian Multicenter Placebo-Controlled Study of Fixed Doses of Risperidone and Haloperidol in the Treatment of Chronic Schizophrenic Patients

CHOUINARD, GUY, JONES, BARRY, REMINGTON, GARY, BLOOM, DAVID, ADDINGTON, DONALD, MacEWAN, G. WILLIAM, LABELLE, ALAIN, BEAUCLAIR, LINDA, ARNOTT, WENDY

Journal:

Journal of Clinical Psychopharmacology

Year:

1993

File:

PDF, 1.44 MB

1993

44

Distinct regulation of cytosolic phospholipase A2 phosphorylation, translocation, proteolysis and activation by tumour necrosis factor-receptor subtypes

JUPP, Orla J., VANDENABEELE, Peter, MacEWAN, David J.

Journal:

Biochemical Journal

Year:

2003

Language:

english

File:

PDF, 270 KB

english, 2003

45

Type II tumour necrosis factor-α receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways

JUPP, Orla J., McFARLANE, Shona M., ANDERSON, Helen M., LITTLEJOHN, Alison F., MOHAMED, Ahmed A. A., MACKAY, Ruth H., VANDENABEELE, Peter, MACEWAN, David J.

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

46

Type II tumour necrosis factor-α receptor (TNFR2) activates c-Jun N-terminal kinase (JNK) but not mitogen-activated protein kinase (MAPK) or p38 MAPK pathways

JUPP, Orla J., McFARLANE, Shona M., ANDERSON, Helen M., LITTLEJOHN, Alison F., MOHAMED, Ahmed A.A., MacKAY, Ruth H., VANDENABEELE, Peter, MacEWAN, David J.

Journal:

Biochemical Journal

Year:

2001

Language:

english

File:

PDF, 312 KB

english, 2001

47

Agonist regulation of adenylate cyclase activity in neuroblastoma × glioma hybrid NG108-15 cells transfected to co-express adenylate cyclase type II and the β 2 -adrenoceptor. Evidence that adenylate cyclase is the limiting component for receptor-mediated stimulation of adenylate cyclase activity

MACEWAN, David J., KIM, Gun-Do, MILLIGAN, Graeme

Journal:

Biochemical Journal

Year:

1996

Language:

english

File:

PDF, 396 KB

english, 1996

48

Arachidonic acid acts through protein kinase C to inhibit depolarization-induced 45 Ca 2+ influx

MacEWAN, DAVID, MITCHELL, RORY

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 259 KB

english, 1990

49

Biological activity of some thyrotrophin-releasing hormone analogues substituted at the 2 position

MITCHELL, RORY, MacEWAN, DAVID, JOHNSON, MELANIE, DOUGAN, LYNNE, BLADON, CHRISTINE

Journal:

Biochemical Society Transactions

Year:

1990

Language:

english

File:

PDF, 276 KB

english, 1990

50

Protein kinase C-dependent and -independent actions of arachidonic acid in GH 3 cells

MacEWAN, DAVID J., MITCHELL, RORY, JOHNSON, MELANIE S., THOMSON, FIONA J.

Journal:

Biochemical Society Transactions

Year:

1991

Language:

english

File:

PDF, 161 KB

english, 1991